Lichen Planopilaris-histologic Criteria & Clues in Vertical Sections

We report on our histological experience in 47 patients with lichen planopilaris/frontal fibrosing alopecia. Besides presenting the spectrum of clinical appearance of the disease we emphasize the importance of vertical histologic sections of biopsies in the clinicopathological work-up of these patients and give precise histologic criteria and clues in different stages of the disease. Immunohistologically, we found a marked reduction of epithelial Ki-67 expression next to the inflammatory process especially evident in advanced stages of disease. *Corresponding author: Michael Wilk, Dermatohistological Laboratory and Private Practice, Postfach 4145, 90021 Nuernberg, Germany, Tel: +49 911 223690; Fax: +49 911 209816; E-mail: [email protected] Received August 29, 2013; Accepted October 03, 2013; Published October 06, 2013 Citation: Wilk M, Zelger BG, Zelger B (2013) Lichen Planopilaris-histologic Criteria & Clues in Vertical Sections. Hair Ther Transplant 3: 111. doi:10.4172/21670951.1000111 Copyright: © 2013 Wilk M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.